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2. Digestive Discomfort: The most commonly reported side effects of NSAID use are gastrointestinal symptoms, including gas, feeling bloated, stomach pain What are the long-term effects of taking Naproxen? Stomach ulcers or ulcers in your gut Gastrointestinal bleeding Serious cardiovascular thrombotic events Experimental data suggest long-term use of ibuprofen/dexibuprofen may reduce the cardioprotective effect of low-dose acetylsalicylic acid ( epsolin er 300 Does Ibuprofen Cause Any Side Effects? Gastrointestinal issues like indigestion and stomach pain Headache Drowsiness Ringing in the ears. What are the side effects of NSAIDs? kidney failure (primarily with chronic use), liver failure, ulcers, and prolonged bleeding after injury or surgery. Long-term effects anaemia due to bleeding in the stomach impaired hearing kidney and liver damage bleeding in the stomach and bowels increased risk of experience persistent headaches. Depending on what’s causing your pain, your doctor may first recommend trying a topical NSAID, such as ibuprofen, ketoprofen

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